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1-SAR-8-ALA ANGIOTENSIN II
Descriptors Found:
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DeCS
Descriptor
English
:
Saralasin
Descriptor
Spanish
:
Saralasina
Descriptor
Portuguese
:
Saralasina
Synonyms
English
:
1-Sar-8-Ala Angiotensin II
1-Sarcosine-8-Alanine Angiotensin II
Tree Number:
D12.644.456.073.041.800
D23.469.050.050.050.700
Definition
English
:
An octapeptide analog of
angiotensin II
(bovine) with
amino acids
1 and 8 replaced with
sarcosine
and
alanine
, respectively. It is a highly specific competitive inhibitor of
angiotensin II
that is used in the
diagnosis
of
HYPERTENSION.
Pharmacological Action:
Angiotensin II Type 1 Receptor Blockers
History Note
English
:
1984(1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23456
Unique Identifier:
D012504
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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